Gene /channels/taxonomy/term/5627/all en Gene targeting helps overcome the resistance of brain cancer to therapy /channels/channels/news/gene-targeting-helps-overcome-resistance-brain-cancer-therapy-323716 <p>New insight into a gene that controls energy production in cancer stem cells could help in the search for a more effective treatment for glioblastoma. A ÁùºÏ²Ê¿ª½±½á¹û-led study published in <i>Nature Communications</i> reveals that suppressing the OSMR gene can improve the effectiveness of radiation therapy.</p> <p>This approach, led by the laboratory of Arezu Jahani-Asl, Assistant Professor of Medicine at ÁùºÏ²Ê¿ª½±½á¹û, was successful in preclinical mouse models where the deletion of the OSMR gene resulted in a significant improvement of tumour response to therapy and expanded lifespan.</p> Mon, 17 Aug 2020 13:12:58 +0000 webfull 162510 at /channels Cystic fibrosis: Promising advances showcased in Montreal /channels/news/cystic-fibrosis-promising-advances-showcased-montreal-265300 <h2>Montreal Gazette Feature:</h2> <p>Read the entire article <a href="http://montrealgazette.com/news/local-news/cystic-fibrosis-promising-advances-showcased-in-montreal">HERE</a>.</p> Mon, 23 Jan 2017 20:01:55 +0000 webfull 124335 at /channels Neuf ans avant d’obtenir un diagnostic de fibrose kystique /channels/news/neuf-ans-avant-d%E2%80%99obtenir-un-diagnostic-de-fibrose-kystique-265301 <h2>Journal de Metro Feature:</h2> <p>Read the entire article <a href="http://journalmetro.com/actualites/national/958953/huit-ans-avant-dobtenir-un-diagnostic-de-fibrose-kystique/">HERE</a>.</p> Mon, 23 Jan 2017 20:03:24 +0000 webfull 124336 at /channels Scientists discover gene behind rare disorders /channels/news/scientists-discover-gene-behind-rare-disorders-218470 <h4>International study with researchers at The Neuro reveals links with other neurodegenerative diseases</h4> <p>MONTREAL, October 9, 2012  - Scientists at the Montreal Neurological Institute and Hospital – The Neuro,  ÁùºÏ²Ê¿ª½±½á¹û working with a team at Oxford University have uncovered the genetic defect underlying a group of rare genetic disorders. </p> Tue, 09 Oct 2012 14:07:58 +0000 webfull 87617 at /channels Attack! Silent watchmen charge to defend the nervous system /channels/news/attack-silent-watchmen-charge-defend-nervous-system-218536 <p>In many pathologies of the nervous system, there is a common event - cells called microglia are activated from surveillant watchmen into fighters.  Microglia are the immune cells of the nervous system, ingesting and destroying pathogens and damaged nerve cells. Until now little was known about the molecular mechanisms of microglia activation despite this being a critical process in the body.</p> Mon, 15 Oct 2012 12:55:57 +0000 webfull 87741 at /channels Des sentinelles silencieuses veillent à la défense du système nerveux /channels/news/des-sentinelles-silencieuses-veillent-%C3%A0-la-d%C3%A9fense-du-syst%C3%A8me-nerveux-218537 <p>Un événement commun se produit dans maintes pathologies du système nerveux : des cellules microgliales, qui sont des sentinelles chargées de surveiller, se muent en combattantes.  Cellules immunitaires du système nerveux, les microglies ingèrent et détruisent des agents pathogènes et des cellules nerveuses lésées. Bien que ce processus soit crucial dans l’organisme, on savait jusqu’à présent très peu au sujet des mécanismes moléculaires d’activation des microglies.</p> Mon, 15 Oct 2012 13:13:18 +0000 webfull 87742 at /channels